RNAi Screening Libraries
Cayman Chemical OrexIn 1 Receptr ReporTR1ea
A linker molecule has been used to conjUGate SN-38 to phlorizin or phloretin to increase the selectivity of SN-38 for cancer cells
Cayman Chemical MelnocortIn4 Receptr Repor 1ea
An MC4R antagonist selectively inhibits [Nle4D-Phe7]-a-MSH binding to recombinant human MC4R over MC1R and MC3R (IC50s 11.63 >10000 and 1115 nM respectively) inhibits a-MSH-induced cAMP production in COS-1 cells expressing human MC4R from 0.1-100 UM reduces stress-induced decreases in the time spent in the light area of the light/dark exploration test in mice reverses restraint stress-induced decreases in food intake in rats
STEMCELL Technologies ArciTect High-Fidelity DNA Pol, 500 Reactions
Polymerase buffers and dNTPs for high-fidelity PCR amplification
Cayman Chemical EP1 Receptr Blockng PeptID 1ea
An internal standard for the quantification of almorexant by GC- or LC-MS
Cayman Chemical PAF Receptr Blockng PeptID 1ea
An inhibitor of microtubule assembly cytotoxic to a variety of cancer cells including SKOV3 ovarian U87 glioblastoma and AsPC-1 pancreatic cancer cells (IC50s 36 77 and 285 nM respectively) induces complete tumor regression in a rat Yoshida AH13 sarcoma model at 10 mg/kg without inducing systemic or neurotoxicity
Cayman Chemical DP1 Receptr Blockng PeptID 1ea
An internal standard for the quantification of cilastatin by GC- or LC-MS